Microbial interference and colonization of the murine gastrointestinal tract by Listeria monocytogenes.

摘要: Abstract Two strains of Listeria monocytogenes, one that formed smooth colonies on agar surfaces and a varient it rough colonies, colonized the gastrointestinal tracts germfree mice. Within 24 h after mice were inoculated orally with about 100 bacteria, population levels per gram (wet weight) tissue both 10(5) to 10(7) in stomach ileum 10(8) 10(9) cecum colon, respectively. As detected Gram-stained histological sections, such gnotobiotes, bacteria lumen all areas tract much mucus layer epithelial surface proximal colon. The strain did not colonize specific-pathogen-free mice, but colonize, same as stomachs bowels ex-germfree previously associated two members indigenous flora (Bacteroides Clostridium). In latter animals, however, listeria form layers colonic epithelium efficiently they monoassociated gnotobiotes.