Rat oligodendrocytes have cell adhesion molecules.

作者: Shama Bhat , Donald H. Silberberg

DOI: 10.1016/0165-3806(85)90240-8

关键词:

摘要: The aggregation of isolated oligodendrocytes appears to be mediated by cell adhesion molecules. molecules are inactivated trypsin. Regeneration the is prevented inhibitors either protein synthesis or glycosylation. An immunological assay described quantitate involved in oligodendrocyte based on following criteria: (a) treatment with rabbit immunoglobulins against oligodendrocyte-conditioned medium their aggregation; and (b) incubation these neutralized ability inhibit aggregation.

参考文章(27)
U Rutishauser, G M Edelman, J P Thiery, R Brackenbury, Adhesion among neural cells of the chick embryo. Progress in Clinical and Biological Research. ,vol. 15, pp. 199- 206 ,(1977)
Michael G. Mage, Preparation of Fab fragments from IgGs of different animal species. Methods in Enzymology. ,vol. 70, pp. 142- 150 ,(1980) , 10.1016/S0076-6879(80)70045-9
J P Thiery, R Brackenbury, U Rutishauser, G M Edelman, Adhesion among neural cells of the chick embryo. II. Purification and characterization of a cell adhesion molecule from neural retina. Journal of Biological Chemistry. ,vol. 252, pp. 6841- 6845 ,(1977) , 10.1016/S0021-9258(17)39926-X
S Hoffman, B C Sorkin, P C White, R Brackenbury, R Mailhammer, U Rutishauser, B A Cunningham, G M Edelman, Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes. Journal of Biological Chemistry. ,vol. 257, pp. 7720- 7729 ,(1982) , 10.1016/S0021-9258(18)34441-7
G M McKhann, K Miller, S E Poduslo, Metabolic properties of maintained oligodendroglia purified from brain. Journal of Biological Chemistry. ,vol. 253, pp. 1592- 1597 ,(1978) , 10.1016/S0021-9258(17)34906-2
R Brackenbury, J P Thiery, U Rutishauser, G M Edelman, Adhesion among neural cells of the chick embryo. I. An immunological assay for molecules involved in cell-cell binding. Journal of Biological Chemistry. ,vol. 252, pp. 6835- 6840 ,(1977) , 10.1016/S0021-9258(17)39925-8
M. Hirn, M. Pierres, H. Deagostini-Bazin, M. Hirsch, C. Goridis, Monoclonal antibody against cell surface glycoprotein of neurons Brain Research. ,vol. 214, pp. 433- 439 ,(1981) , 10.1016/0006-8993(81)91208-7
S. Szuchet, S. H. Yim, S. Monsma, Lipid metabolism of isolated oligodendrocytes maintained in long-term culture mimics events associated with myelinogenesis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 80, pp. 7019- 7023 ,(1983) , 10.1073/PNAS.80.22.7019
Isabelle Lubetzki-Korn, Haim Ovadia, Israel Vlodavsky, Zvi Fuks, Oded Abramsky, Enhanced growth and morphological differentiation of isolated adult rat oligodendrocytes in vitro: use of a naturally produced extracellular matrix Brain Research. ,vol. 267, pp. 151- 155 ,(1983) , 10.1016/0006-8993(83)91049-1
G. Edelman, Cell adhesion molecules Science. ,vol. 219, pp. 450- 457 ,(1983) , 10.1126/SCIENCE.6823544