SINUS HISTIOCYTOSIS WITH MASSIVE LYMPHADENOPATHY (ROSAI-DORFMAN DISEASE)

摘要: The term "sinus histiocytosis with massive lymphadenopathy," introduced in 1969 by Rosai and Dorfman, refers to a newly recognized disease entity characterized painless cervical lymphadenopathy, fever, leukocytosis, increased erythrocyte sedimentation rate, hypergammaglobulinemia. typical course is one of insidious onset, protracted duration the active state, eventual spontaneous remission, occasionally subsequent recurrences. Lymph nodes other than those area may be involved, extranodal involvement can occur (such as orbit, skin, or respiratory tract). Clinically, this closely simulate malignant lymphoma nonneoplastic conditions lymphadenopathy. We present case which process extensively involved tract produced obstructive symptoms. otorhinolaryngologist should aware include it differential diagnosis for patients lymph node enlargement bronchial obstruction.