ジおよびトリ置換フェニル=N-(6-メトキシ-2-ピリジル)-N-メチルカーバメート誘導体の除草活性

摘要: Forty-nine di- and tri-substituted-phenyl N-(6-methoxy-2-pyridyl)-N-methylcarbamates thiono-type thiocarbamates were synthesized. Their herbicidal phytotoxic activities against barnyardgrass rice plants evaluated under paddy field conditions to determine the relationships between chemical structure activity.Points identified as important for most suitable obtain activity follows:1. When two substituents introduced into phenoxy residue in O-phenyl N-(6-methoxy-2-pyridyl)-N-methylthiocarbamates, was strongly affected by their substituted position. dichloro dimethyl groups used substituents, 3, 4-di-substituted derivatives showed highest activity. No observed when one of bonded 2-position on ring.2. Comparison 4-di- 4, 5-tri-substituted-phenyl former exhibit stronger than latter.3. Among 4-substituents phenyl ring carbamates, 3-alkyl-4-halogeno 4-dialkyl high activity, while among derivatives, O-4-tert-butyl-3-methylphenyl thiocarbamate highest.4. Many compounds 3-alkyl -4-halogeno group In case 3-methyl 3-ethyl exhibited carbamates; 3-isopropyl 3-tert-butyl other hand, similar.5. The results structure-activity correlation analysis adaptive least-squares method O-3, 4-di-substituted-phenyl that adequate hydrophobic steric are preferable activity.6. For highly active compounds, at 1.5 leaf stage also examined, some similar pyributicarb.