作者: Carla Gentili , Ornella Sanfilippo , Rosella Silvestrini
DOI: 10.1002/1097-0142(19810815)48:4<974::AID-CNCR2820480420>3.0.CO;2-#
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摘要: The relationship between primary tumor proliferative activity and clinical pathologic characteristics was analyzed in relation to menopausal status for 541 breast cancer patients. thymidine-3H labeling index (LI) showed significantly higher median values cancers from premenopausal (4.2%) paramenopausal patients comparison that of postmenopausal (1.8%) LI not generally correlated size. only significant correlation limited tumors with negative axillary lymph nodes neither the presence nor extension metastasis. prognostic significance assessed 145 untreated without metastases. A value observed who relapsed (5.7%) within 52 months than those did relapse (2%). However, difference statistically (P less 0.01) patients, but Similarly, a 0.0005) rate (67.4%) had above 4.6% (0%) below No risk