Atypical ganglioneurocytoma: case report and review of literature

摘要: Extra-ventricular neurocytoma (EVN) is a distinct neuro-pathological entity that has received increasing attention as the routine use of immunohistochemical staining helped to distinguish it from oligodendroglioma; its more common morphologic mimic. Ganglionic differentiation in parts tumor common, hence lending name Ganglioneurocytoma. Generally considered low-grade tumors, recent literature highlights clinical examples with atypical pathologic features elevate grade these tumors World Health Organization (WHO) III and portend worse prognosis. Biological progression higher grade, serially over time same patient, not been previously described. We report case ganglioneurocytoma (WHO II) recurred increased proliferation index III). This illustrates challenges involved precise grading tumors. Also exemplified unpredictable potential seemingly lesions. Gross total resection follow-up are essential for optimum treatment, EVNs associated prognosis than their intra-ventricular counterparts.