Validation of the Charlson Comorbidity Index in Acutely Hospitalized Elderly Adults: A Prospective Cohort Study
作者： Wijnanda J. Frenkel , Erika J. Jongerius , Miranda J. Mandjes-van Uitert , Barbara C. van Munster , Sophia E. de Rooij
DOI: 10.1111/JGS.12635
关键词:
摘要: Objectives To determine whether the Charlson Comorbidity Index (CCI) predicts short- and long-term mortality. Design Prospective cohort study. Setting The medical department of two university hospitals one community-based hospital. Participants Acutely hospitalized individuals aged 65 older with a mean age 77.8 ± 7.9, 45.8% male (n = 1,313). Measurements In eligible persons, information on demographic characteristics, activities daily living (modified Katz ADL score), disease-related measures was collected within 48 hours after admission. Follow-up using self-reporting questionnaires performed at 3 months 1 year. Functional decline defined as least point modified score 12 from baseline. Mortality data 5 years were municipal database. Results Logistic regression analysis, adjusted for sex, showed that participants CCI or more had higher 3-month (odds ratio (OR) 3.6, 95% confidence interval (CI) 2.1�6.4), 1-year (OR 7.1, CI 4.2�11.9), 5-year 52.4, 13.3�206.4) mortality than those 0. Participants scores between 4 also greater risk years. Conclusion independently in acutely ill elderly adults.
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