Mesenchymal stem cell infusion shows promise for combating coronavirus (COVID-19)-induced pneumonia

作者: Ashok K Shetty , None

DOI: 10.14336/AD.2020.0301

关键词:

摘要: A new study published by the journal Aging & Disease reported that intravenous administration of clinical-grade human mesenchymal stem cells (MSCs) into patients with coronavirus disease 2019 (COVID-19) resulted in improved functional outcomes (Leng et al., Dis, 11:216-228, 2020). This demonstrated infusion MSCs is a safe and effective approach for treating COVID-19 pneumonia, including elderly displaying severe pneumonia. acute respiratory illness caused named syndrome 2 (SARS-CoV-2). Currently, patients, particularly those afflicted challenging as no specific drugs or vaccines against SARS-CoV-2 are available. Therefore, MSC therapy inhibiting overactivation immune system promoting endogenous repair improving lung microenvironment after infection found this striking. Additional studies larger cohort needed to validate therapeutic intervention further, however.

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