Passive biaxial mechanical properties of the rat bladder wall after spinal cord injury.
作者： D. CLAIRE GLOECKNER , MICHAEL S. SACKS , MATTHEW O. FRASER , GEORGE T. SOMOGYI , WILLIAM C. de GROAT
DOI: 10.1016/S0022-5347(05)65137-3
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摘要: Purpose: Changes in the mechanical properties of bladder wall after spinal cord injury can alter compliance and tension, leading to changes afferent nerve activity abnormal reflex mechanisms. To our knowledge we report first application biaxial testing normal demonstrate how these change injury.Materials Methods: Whole bladders were harvested from mature female Sprague-Dawley rats weighing 250 300 gm. Test group animals underwent complete transection at T9 T10 level comprised control group. The cut open longitudinally, trigone apex removed remaining tissue was trimmed a square 9 13 mm. per side. Mechanical sample tested using planar testing, which stress applied circumferential longitudinal (base-apex) directions, resulting axial strains measured.Resul...
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