Effect of obesity and other lifestyle factors on mortality in women with breast cancer.

作者: Luigino Dal Maso , Antonella Zucchetto , Renato Talamini , Diego Serraino , Carmen F Stocco

DOI: 10.1002/IJC.23747

关键词:

摘要: A few lifestyle characteristics before cancer diagnosis have been suggested to modify the prognosis of breast cancer. Follow-up information from 1,453 women with incident invasive cancer, diagnosed between 1991 and 1994 interviewed within framework an Italian multicenter case-control study, was used assess effect obesity a large spectrum other factors on mortality. Five hundred three deaths, including 398 were identified. Hazard ratios (HR) for all-cause mortality corresponding 95% confidence intervals (CI), calculated using Cox proportional hazards models adjusted age (stage receptor status). Increased risk death emerged body mass index (BMI) >/= 30 kg/m(2) (HR = 1.38; CI: 1.02-1.86), compared /= 0.85 1.27; 0.98-1.64), /=30 high WHR (>/=0.85), BMI /=55 years age, whereas it stronger in I-II stage than III-IV Low vegetable fruit consumption current or past smoking also associated marginally worse survival. No significant relationship survival after several major factors, physical activity, alcohol drinking, exogenous hormones use fat intake. High factor that most consistently modified our study.

参考文章(41)
E. Steliarova-Foucher, M. Laversanne, J. Ferlay, D. Forman, S. Antoni, Freddie Ian Bray, C. Gombe Mbalawa, B. Kohler, M. Piñeros, D. H. Brewster, I. Soerjomataram, R. Swaminathan, Cancer Incidence in Five Continents ,(1997)
Jennifer M. Petrelli, Eugenia E. Calle, Carmen Rodriguez, Michael J. Thun, Body mass index, height, and postmenopausal breast cancer mortality in a prospective cohort of US women Cancer Causes & Control. ,vol. 13, pp. 325- 332 ,(2002) , 10.1023/A:1015288615472
David R. Cox, Regression Models and Life-Tables Springer Series in Statistics. ,vol. 34, pp. 527- 541 ,(1992) , 10.1007/978-1-4612-4380-9_37
Silvia Franceschi, Adriano Favero, Carlo La Vecchia, Anna E. Barón, Eva Negri, Luigino Dal Maso, Attilio Giacosa, Maurizio Montella, Ettore Conti, Dino Amadori, Body size indices and breast cancer risk before and after menopause International Journal of Cancer. ,vol. 67, pp. 181- 186 ,(1996) , 10.1002/(SICI)1097-0215(19960717)67:2<181::AID-IJC5>3.0.CO;2-P
Sven Törnberg, John Carstensen, Serum beta-lipoprotein, serum cholesterol and Quetelet's index as predictors for survival of breast cancer patients European Journal of Cancer. ,vol. 29, pp. 2025- 2030 ,(1993) , 10.1016/0959-8049(93)90466-S
R. Talamini, S. Franceschi, C. La Vecchia, E. Negri, L. Borsa, M. Montella, F. Falcini, E. Conti, C. Rossi, The role of reproductive and menstrual factors in cancer of the breast before and after Menopause European Journal of Cancer. ,vol. 32, pp. 303- 310 ,(1996) , 10.1016/0959-8049(95)00615-X
Sharon K. Sagiv, Mia M. Gaudet, Sybil M. Eng, Page E. Abrahamson, Sumitra Shantakumar, Susan L. Teitelbaum, Julie A. Britton, Paula Bell, Joyce A. Thomas, Alfred I. Neugut, Regina M. Santella, Marilie D. Gammon, Active and Passive Cigarette Smoke and Breast Cancer Survival Annals of Epidemiology. ,vol. 17, pp. 385- 393 ,(2007) , 10.1016/J.ANNEPIDEM.2006.11.004
Eva Negri, Claudia Braga, Carlo La Vecchia, Silvia Franceschi, Fabio Parazzini, Family history of cancer and risk of breast cancer International Journal of Cancer. ,vol. 72, pp. 735- 738 ,(1997) , 10.1002/(SICI)1097-0215(19970904)72:5<735::AID-IJC5>3.0.CO;2-T
Janet R. Daling, Kathleen E. Malone, David R. Doody, Lisa G. Johnson, Julie R. Gralow, Peggy L. Porter, Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma. Cancer. ,vol. 92, pp. 720- 729 ,(2001) , 10.1002/1097-0142(20010815)92:4<720::AID-CNCR1375>3.0.CO;2-T