Preferential formation of (2'–5')-linked internucleotide bonds in non-enzymatic reactions
作者： R. Lohrmann , L.E. Orgel
DOI: 10.1016/0040-4020(78)88129-0
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摘要: Abstract The reactions of ImpU with MepU, MepC, MepA and MepG in aqueous solution yield mixtures isomeric dinucleotides which the (2'–5') linked compound is 6–9 times more abundant than (3'–5')-linked compound. ratio isomers obtained from ImpA under these conditions similar, but increases to 18 when a poly(U) template included reaction mixture.
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