TDP-43 post-translational modifications in health and disease.

Chihana Kabuta, Kanako Kono, Keiji Wada, Tomohiro Kabuta, 4-Hydroxynonenal induces persistent insolubilization of TDP-43 and alters its intracellular localization Biochemical and Biophysical Research Communications. ,vol. 463, pp. 82- 87 ,(2015) , 10.1016/J.BBRC.2015.05.027

Ki Yoon Kim, Hee-Woo Lee, Yu-mi Shim, Inhee Mook-Jung, Gye Sun Jeon, Jung-Joon Sung, A phosphomimetic mutant TDP-43 (S409/410E) induces Drosha instability and cytotoxicity in Neuro 2A cells. Biochemical and Biophysical Research Communications. ,vol. 464, pp. 236- 243 ,(2015) , 10.1016/J.BBRC.2015.06.125

Johannes Brettschneider, Kelly Del Tredici, Jon B. Toledo, John L. Robinson, David J. Irwin, Murray Grossman, EunRan Suh, Vivianna M. Van Deerlin, Elisabeth M. Wood, Young Baek, Linda Kwong, Edward B. Lee, Lauren Elman, Leo McCluskey, Lubin Fang, Simone Feldengut, Albert C. Ludolph, Virginia M.-Y. Lee, Heiko Braak, John Q. Trojanowski, Stages of pTDP-43 pathology in amyotrophic lateral sclerosis Annals of Neurology. ,vol. 74, pp. 20- 38 ,(2013) , 10.1002/ANA.23937

Owen A. Brady, Peter Meng, Yanqiu Zheng, Yuxin Mao, Fenghua Hu, Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1. Journal of Neurochemistry. ,vol. 116, pp. 248- 259 ,(2011) , 10.1111/J.1471-4159.2010.07098.X

Fabiola Rojas, David Gonzalez, Nicole Cortes, Estibaliz Ampuero, Diego E. Hernández, Elsa Fritz, Sebastián Abarzua, Alexis Martinez, Alvaro A. Elorza, Alejandra Alvarez, Felipe Court, Brigitte van Zundert, Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling Frontiers in Cellular Neuroscience. ,vol. 9, pp. 203- 203 ,(2015) , 10.3389/FNCEL.2015.00203

Todd J Cohen, Andrew W Hwang, Travis Unger, John Q Trojanowski, Virginia M Y Lee, Redox signalling directly regulates TDP‐43 via cysteine oxidation and disulphide cross‐linking The EMBO Journal. ,vol. 31, pp. 1241- 1252 ,(2012) , 10.1038/EMBOJ.2011.471

Carolina Ceballos-Diaz, Awilda M. Rosario, Hyo-Jin Park, Paramita Chakrabarty, Amanda Sacino, Pedro E. Cruz, Zoe Siemienski, Nicolas Lara, Corey Moran, Natalia Ravelo, Todd E. Golde, Nikolaus R. McFarland, Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice. Molecular Neurodegeneration. ,vol. 10, pp. 25- 25 ,(2015) , 10.1186/S13024-015-0026-7

Oliver Pagel, Stefan Loroch, Albert Sickmann, René P Zahedi, Current strategies and findings in clinically relevant post-translational modification-specific proteomics. Expert Review of Proteomics. ,vol. 12, pp. 235- 253 ,(2015) , 10.1586/14789450.2015.1042867

Besa Ziso, Tim L. Williams, R. Jon L. Walters, Stephan R. Jaiser, Johannes Attems, Udo C. Wieshmann, A.J. Larner, Anu Jacob, Facial Onset Sensory and Motor Neuronopathy: Further Evidence for a TDP-43 Proteinopathy. Case Reports in Neurology. ,vol. 7, pp. 95- 100 ,(2015) , 10.1159/000381944

Vincent Picher-Martel, Kallol Dutta, Daniel Phaneuf, Gen Sobue, Jean-Pierre Julien, Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells Molecular Brain. ,vol. 8, pp. 71- 71 ,(2015) , 10.1186/S13041-015-0162-6