Interdependence of tetrapyrrole metabolism, the generation of oxidative stress and the mitigative oxidative stress response

摘要: Tetrapyrroles are involved in light harvesting and perception, electron-transfer reactions, as co-factors for key enzymes sensory proteins. Under conditions which cells exhibit stress-induced imbalances of photosynthetic or absorption exceeds the ability cell to use photoexcitation energy synthesis redox imbalance can occur cells. Such lead generation reactive oxygen species (ROS) associated with alterations tetrapyrrole homeostasis. ROS accumulation result cellular damage detrimental effects on organismal fitness, molecules serve signals induce a protective damage-mitigating oxidative stress signaling response Induced responses include tetrapyrrole-dependent -independent mechanisms mitigating and/or accumulation. Thus, tetrapyrroles be contributors stress, but also essential protect by contributing detoxification ROS. In this review, we highlight interconnection interdependence metabolism occurrence organisms.