Process for preparing glucagon or fragments or derivatives thereof in yeast

作者: Mogens T. Hansen , Alister J. Moody , Fanny Norris , Lars Thim , Kjeld Norris

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摘要: Glucagon or fragments derivatives thereof are prepared by cultivation of a yeat strain transformed with replicable expression vehicle comprising gene encoding the such products. Synthetic genes glucagon have been constructed. Also provided vehicles replication system for providing stable maintenance in yeast and DNA-sequence transformant strains containing vehicles.

参考文章(4)
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P. K. Lund, R. H. Goodman, P. C. Dee, J. F. Habener, Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 79, pp. 345- 349 ,(1982) , 10.1073/PNAS.79.2.345