Silver-catalyzed direct spirocyclization of alkynes with thiophenols: a simple and facile approach to 3-thioazaspiro[4,5]trienones

作者: Huanhuan Cui , Wei Wei , Daoshan Yang , Jimei Zhang , Zhihong Xu

DOI: 10.1039/C5RA16548B

关键词:

摘要: A new and convenient silver-catalyzed direct oxidative spirocyclization of alkynes with thiophenols is described. This methodology provides a simple practical approach to various 3-thioazaspiro[4,5]trienones in moderate good yields high atom efficiency excellent functional group tolerance.

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