作者: Nerea Martin-Calvo , Miguel-Angel Martínez-González , Maira Bes-Rastrollo , Alfredo Gea , Ma Carmen Ochoa
DOI: 10.1017/S136898001300356X
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摘要: Department of Food Sciences and Physiology, School Pharmacy, University ofNavarra, Pamplona, SpainSubmitted 10 May 2013: Final revision received 30 September Accepted 19 December 2013AbstractObjective: To assess the association between consumption sugar-sweetenedcarbonated beverages (SSCB) obesity in children adolescents from Navarra(Spain).Design: We used a matched case–control study design. The exposure, SSCB con-sumption (1 serving: 200ml), was measured with previously validated FFQ.Anthropometrical measuresweretakenusing standardized protocols. Theoutcome,obesity, defined as BMI above age- sex-specific 97th percentileaccording to Spanish reference charts. In analysis we conditionallogistic regression. Potential confounders were controlled using multivariablemodel.Setting: Subjects recruited paediatric departments Universidad deNavarra Clinic Navarra Hospital Complex, three primary healthcentres Navarra. Controls when attending for routine medicalexamination or vaccination.Subjects: One hundred seventy-four obese 174 individuallysex- age-matched controls, 52?87% boys, mean age 11?6years.Exclusion criteria dietary interventions, exposure hormone treatment,development secondary due endocrinopathy serious intercurrentillness.Results: Independently other factors, high (.4servings/week) significantly associated (OR53?46; 95% CI 1?24, 9?62;P50?01). Besides, each additionaldaily serving 69%relative increase risk (OR51?69; 1?04, 2?73; P50?03).Conclusions: found strong significant risk. Our results suggest monotonic dose–response linearshape this (P trend50?02).KeywordsSoft drinksSodaChildrenObesityObesity is chronic disease that an imbalanceof energy homeostasis. mechanisms underlying thismetabolic disorder reflect complex interactions genetic,environmental behavioural factors. Many studies sug-gest increases many chronicdiseases such type 2 diabetes, metabolic syndrome orsome types cancer, becoming earlier inlife clearly amplifies increasing prevalence ofobesity among has become animportant public health problem priority issue forauthorities