Radiologic and pathologic features of a primary chloroma of the testis: a case report and brief review of the literature.

作者: E Pazarli , St Pervana , I Tsitouridis , E P Kariki , Ch Maskalidis

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摘要: Aim: To describe a case of primary granulocytic sarcoma. Case description: A 43-year-old man presented with painless testicular swelling. There was no previous history malignancy or hematologic disease. Ultrasound and magnetic resonance imaging examination showed an intratesticular mass extending to the surrounding scrotal tissues including epididymis. Inguinal radical orchiectomy followed by macroscopic microscopic evaluation tumor. Immunohistochemistry demonstrated strong positivity neoplastic cells for leucocyte common antigen (LCA), myeloperoxidase, CD-34 CD-117. All laboratory tests metastatic disease, bone marrow biopsy, were negative, leading diagnosis sarcoma testis. Conclusion: Although chloromas usually manifest in patients malignancy, isolated cases may occur. The low specificity and, occasionally, is challenging right diagnosis. role immunohistochemistry conjunction clinical, findings crucial reach correct Hippokratia 2014; 18 (4): 366-369.

参考文章(19)
Economopoulos T, Papageorgiou E, Anagnostou D, Constantinidou M, Alexopoulos C, Stathakis N, Primary granulocytic sarcoma of the testis. Leukemia. ,vol. 8, pp. 199- 200 ,(1994)
Fatma Markoc, Nazan Bozdogan, Fisun Ardic Yükrük, Evrim Berkel Gumuc, Noyan Can Akdur, Granulocytic sarcomas: difficulties in diagnosis. Tumori. ,vol. 96, pp. 149- 153 ,(2010) , 10.1177/030089161009600124
R H Young, J A Ferry, J R Srigley, Granulocytic sarcoma of the testis: a report of two cases of a neoplasm prone to misinterpretation. Modern Pathology. ,vol. 10, pp. 320- 325 ,(1997)
BRADY R. WALKER, PATRICK C. CARTWRIGHT, GRANULOCYTIC SARCOMA PRESENTING AS TESTICULAR AND PARATESTICULAR MASSES IN INFANCY The Journal of Urology. ,vol. 165, pp. 224- 224 ,(2001) , 10.1097/00005392-200101000-00064
Shih-Wen Hu, Sheau-Fang Yang, Chee-Yin Chai, Shu-Pin Huang, Chloroma of the testis after allogeneic peripheral blood stem cell transplantation: a case report. Kaohsiung Journal of Medical Sciences. ,vol. 20, pp. 506- 511 ,(2004) , 10.1016/S1607-551X(09)70250-5
J. Constantinou, T. Nitkunan, M. Al-Izzi, T.A. McNicholas, Testicular granulocytic sarcoma, a source of diagnostic confusion. Urology. ,vol. 64, pp. 807- 809 ,(2004) , 10.1016/J.UROLOGY.2004.05.021
M H Pui, B D Fletcher, J W Langston, Granulocytic sarcoma in childhood leukemia: imaging features. Radiology. ,vol. 190, pp. 698- 702 ,(1994) , 10.1148/RADIOLOGY.190.3.8115614
Richard S. Neiman, Maurice Barcos, Costan Berard, Hugh Bonner, Risa Mann, Robert E. Rydell, John M. Bennett, Granulocytic sarcoma: A clinicopathologic study of 61 biopsied cases Cancer. ,vol. 48, pp. 1426- 1437 ,(1981) , 10.1002/1097-0142(19810915)48:6<1426::AID-CNCR2820480626>3.0.CO;2-G
Kevin R Imrie, Michael J Kovacs, Debbie Selby, Jeffrey Lipton, Bruce J Patterson, Dominic Pantalony, Peeter Poldre, Bo-Yee Ngan, Armand Keating, Isolated Chloroma: The Effect of Early Antileukemic Therapy Annals of Internal Medicine. ,vol. 123, pp. 351- 353 ,(1995) , 10.7326/0003-4819-123-5-199509010-00005