作者: Rony Dev , Egidio Del Fabbro , Shalini Dalal
DOI: 10.1097/SPC.0000000000000464
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摘要: Purpose of review Cancer cachexia cannot be easily reversed by standard nutritional support and interventions directed at underlying metabolic derangements may needed to prevent or reverse maintain healthy body composition. The following will highlight the contribution potential therapeutic for insulin resistance, alterations in ghrelin signaling, hypogonadism cancer patients. Recent findings In addition decreased caloric intake, chronic inflammation, altered metabolism glucose, proteins lipids, endocrine abnormalities can propagate weight loss changes composition Summary cachexia, muscle mass with without fat mass, is a multifactorial syndrome, which associated increased morbidity mortality. Currently, limited options treatment patients exist, lead clinically meaningful improvements gain performance status. Treatment low testosterone, sensitivity, future, lean cachexia.