Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization
作者： Ying-Cing Lin , Duen-Yi Huang , Jang-Shiun Wang , Yi-Ling Lin , Shie-Liang Hsieh
DOI: 10.1189/JLB.3HI0814-371RR
关键词:
摘要: … of ASC is a critical step for caspase-1 activation; therefore, we investigated whether … ASC oligomer formation is regulated by the activation of Syk. As a result, we showed that the ASC …
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