Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors
作者： K. V. Gurova , J. E. Hill , C. Guo , A. Prokvolit , L. G. Burdelya
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摘要: … knockdown of Mdm2 did not lead to p53 reac- … us to exclude Mdm2 targeting as the mechanism of the p53-activating effect of 9AA. The accumulation of unphosphorylated p53 is the …
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