Stilbamidine Isethionate Therapy of Tic Douloureux

摘要: LASSICAL tic douloureux is a disease of unknown origin characterized, among other attributes, by periods spontaneous remission. Any proposed medical therapy must therefore be scrutinized with specific attention to this factor. Previous attempts at relief, such as that assigned the intake massive doses ferrous carbonate 9,1~ or injection B121,11 have failed alter substantially natural course disease. The inhalation trichloroethylene offers best momentary relief obtained short-acting analgesic agent. ~9 severe pain relieved permanently only complete section sensory root trigeminal nerve. time-tested procedures temporal route Spiller-Frazier 25 cerebellar approach Dandy 7 carry virtually no mortality in experienced hands and scant morbidity. Following there remain, however, permanent analgesia anesthesia over domain fifth nerve, including cornea. procedure scarcely applicable cases bilateral alternating can applied younger age group patients extreme reluctance. More peripherally placed nerve sections alcohol injections are effective measures for temporary douloureux. recently, decompression ganglion has been Taarnhoj 27 means relieving same time avoiding subjective distress loss face potential danger corneal sensitivity. operation ganglionlysis variation on theme. 21,26 Whether based upon sound premises not, not unlike partial once advocated Frazier 12 s recurrence rate these newer also high. 17,2s In 194~, Napier Sen Gupta described late chronic neuropathy confined largely distribution which occurred an unexpected sequel administration 4:4'-diamidino-diphenyl-ethylene kala-azar. observation was extended 22 others 2,5,6,2~ treated kala-azar, trypanosomiasis blastomycosis. majority therapeutic stil