Racial and ethnic differences in COVID-19 vaccine hesitancy and uptake

作者: Tim D Spector , David A Drew , Claire J Steves , Carole H Sudre , Sebastien Ourselin

DOI: 10.1101/2021.02.25.21252402

关键词:

摘要: Background Racial and ethnic minorities have been disproportionately impacted by COVID-19. In the initial phase of population-based vaccination in United States (U.S.) Kingdom (U.K.), vaccine hesitancy limited access may result disparities uptake. Methods We performed a cohort study among U.S. U.K. participants smartphone-based COVID Symptom Study (March 24, 2020-February 16, 2021). used logistic regression to estimate odds ratios (ORs) COVID-19 (unsure/not willing) receipt. Results (n=87,388), compared White non-Hispanic participants, multivariable ORs were 3.15 (95% CI: 2.86 3.47) for Black 1.42 (1.28 1.58) Hispanic 1.34 (1.18 1.52) Asian 2.02 (1.70 2.39) reporting more than one race/other. (n=1,254,294), racial had similarly elevated hesitancy: their corresponding 2.84 2.69 2.99) 1.66 (1.57 1.76) South 1.84 1.98) Middle East/East 1.48 (1.39 1.57) Among OR receipt was 0.71 (0.64 0.79) disparity that persisted individuals who specifically endorsed willingness obtain vaccine. contrast, uptake not observed Conclusions greater minorities, living less likely receive participants. Lower during rollout is attributable both access.

参考文章(16)
Ezekiel J Emanuel, Christine C Grady, Robert A Crouch, Reidar K Lie, Franklin G Miller, David D Wendler, The Oxford Textbook of Clinical Research Ethics ,(2008)
Todd C. Knepper, Howard L. McLeod, When will clinical trials finally reflect diversity Nature. ,vol. 557, pp. 157- 159 ,(2018) , 10.1038/D41586-018-05049-5
David A Drew, Long H Nguyen, Claire J Steves, Cristina Menni, Maxim Freydin, Thomas Varsavsky, Carole H Sudre, M Jorge Cardoso, Sebastien Ourselin, Jonathan Wolf, Tim D Spector, Andrew T Chan, COPE Consortium, None, Rapid implementation of mobile technology for real-time epidemiology of COVID-19. Science. ,vol. 368, pp. 1362- 1367 ,(2020) , 10.1126/SCIENCE.ABC0473
Eboni G. Price-Haywood, Jeffrey Burton, Daniel Fort, Leonardo Seoane, Hospitalization and Mortality among Black Patients and White Patients with Covid-19. The New England Journal of Medicine. ,vol. 382, pp. 2534- 2543 ,(2020) , 10.1056/NEJMSA2011686
Chun-Han Lo, Long H Nguyen, David A Drew, Mark S Graham, Erica T Warner, Amit D Joshi, Christina M Astley, Chuan-Guo Guo, Wenjie Ma, Raaj S Mehta, Sohee Kwon, Mingyang Song, Richard Davies, Joan Capdevila, Karla A Lee, Mary Ni Lochlainn, Thomas Varsavsky, Carole H Sudre, Jonathan Wolf, Yvette C Cozier, Lynn Rosenberg, Lynne R Wilkens, Christopher A Haiman, Loic Le Marchand, Julie R Palmer, Tim D Spector, Sebastien Ourselin, Claire J Steves, Andrew T Chan, COPE Consortium, Racial and ethnic determinants of Covid-19 risk medRxiv. ,(2020) , 10.1101/2020.06.18.20134742
Cary P. Gross, Utibe R. Essien, Saamir Pasha, Jacob R. Gross, Shi-yi Wang, Marcella Nunez-Smith, Racial and Ethnic Disparities in Population-Level Covid-19 Mortality. Journal of General Internal Medicine. ,vol. 35, pp. 3097- 3099 ,(2020) , 10.1007/S11606-020-06081-W
Anand Shah, Peter W. Marks, Stephen M. Hahn, Unwavering Regulatory Safeguards for COVID-19 Vaccines. JAMA. ,vol. 324, pp. 931- 932 ,(2020) , 10.1001/JAMA.2020.15725
Pinar Karaca-Mandic, Archelle Georgiou, Soumya Sen, Assessment of COVID-19 Hospitalizations by Race/Ethnicity in 12 States. JAMA Internal Medicine. ,vol. 181, pp. 131- 134 ,(2021) , 10.1001/JAMAINTERNMED.2020.3857
Paul L. Reiter, Michael L. Pennell, Mira L. Katz, Acceptability of a COVID-19 vaccine among adults in the United States: How many people would get vaccinated? Vaccine. ,vol. 38, pp. 6500- 6507 ,(2020) , 10.1016/J.VACCINE.2020.08.043
Kimberly A. Fisher, Sarah J. Bloomstone, Jeremy Walder, Sybil Crawford, Hassan Fouayzi, Kathleen M. Mazor, Attitudes Toward a Potential SARS-CoV-2 Vaccine: A Survey of U.S. Adults. Annals of Internal Medicine. ,vol. 173, pp. 964- 973 ,(2020) , 10.7326/M20-3569