Current Progress in Synthetic Genetic Networks

作者: Amir Pandi , Heykel Trabelsi

DOI: 10.1007/978-981-15-0081-7_2

关键词:

摘要: Synthetic genetic networks are the main and most-studied area of synthetic biology. Biological or circuits provide modular scalable tools to design-build-test biological systems for medical, environmental, industrial applications. This chapter focuses on introducing discussing recent progress in design application such devices. starts with classification role each their pros cons. Then, applications digital/analog genetic/metabolic presented three groups smart therapeutics, diagnosis, metabolic engineering. Finally, methods implementing different classes gene covering majority developed methodologies so far. brings a complete introduction advances audience who aim get familiar this fast-growing technology.

参考文章(146)
Xiao Wang, Liang Zhao, Kong-Nan Zhao, An Optimized Yeast Cell-Free Lysate System for In Vitro Translation of Human Virus mRNA Methods in Molecular Biology. ,vol. 1118, pp. 219- 230 ,(2014) , 10.1007/978-1-62703-782-2_14
Di Liu, Trent Evans, Fuzhong Zhang, Applications and advances of metabolite biosensors for metabolic engineering Metabolic Engineering. ,vol. 31, pp. 35- 43 ,(2015) , 10.1016/J.YMBEN.2015.06.008
Manish Kushwaha, Howard M. Salis, A portable expression resource for engineering cross-species genetic circuits and pathways Nature Communications. ,vol. 6, pp. 7832- 7832 ,(2015) , 10.1038/NCOMMS8832
Marie F. La Russa, Lei S. Qi, The New State of the Art: Cas9 for Gene Activation and Repression. Molecular and Cellular Biology. ,vol. 35, pp. 3800- 3809 ,(2015) , 10.1128/MCB.00512-15
Miao Ding, Rong Li, Rong He, Xingyong Wang, Qijian Yi, Weidong Wang, p53 activated by AND gate genetic circuit under radiation and hypoxia for targeted cancer gene therapy Cancer Science. ,vol. 106, pp. 1163- 1173 ,(2015) , 10.1111/CAS.12739
Brynne C Stanton, Alec A K Nielsen, Alvin Tamsir, Kevin Clancy, Todd Peterson, Christopher A Voigt, Genomic mining of prokaryotic repressors for orthogonal logic gates. Nature Chemical Biology. ,vol. 10, pp. 99- 105 ,(2014) , 10.1038/NCHEMBIO.1411
Arthur Prindle, Jangir Selimkhanov, Tal Danino, Phillip Samayoa, Anna Goldberg, Sangeeta N. Bhatia, Jeff Hasty, Genetic Circuits in Salmonella typhimurium ACS Synthetic Biology. ,vol. 1, pp. 458- 464 ,(2012) , 10.1021/SB300060E
David Bikard, Chad W Euler, Wenyan Jiang, Philip M Nussenzweig, Gregory W Goldberg, Xavier Duportet, Vincent A Fischetti, Luciano A Marraffini, Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials Nature Biotechnology. ,vol. 32, pp. 1146- 1150 ,(2014) , 10.1038/NBT.3043
Wei Deng, Huaguo Xu, Wei Ding, Haojun Liang, DNA Logic Gate Based on Metallo-Toehold Strand Displacement PLoS ONE. ,vol. 9, pp. e111650- ,(2014) , 10.1371/JOURNAL.PONE.0111650