Management of acute Achilles tendinopathy: effect of etoricoxib on pain control and leg stiffness.

摘要: Tendinopathies are a major cause of disability in the athletic population; main purpose treatment these injuries is to reduce pain and improve function promptly. The objective this randomized, active comparator controlled, blinded study was evaluate etoricoxib efficacy control leg stiffness athletes suffering acute unilateral Achilles tendinopathy. Fifty-six eligible male (mean age 37.5 ± 11.0 y) tendinopathy were randomized receive either 120 mg oral once daily (n=28) or diclofenac 100 (n=28). Pain (100-mm visual analogue scale-VAS), analgesic effect (percentage 100-mm VAS reduction), satisfaction with management (PGART), (LSR) evaluated after one week anti-inflammatory treatment. Over 7-day period, both provided significantly relief tendon compared that experienced at baseline 26.7 2.2 56.4 1.8, respectively; p<.001). Analgesic averaged 53.7 38.1% (etoricoxib= 56.4% 50.6%, p=0.64). Patients referred high level (PGART = 2.0 1.3), while showed significant improvement one-week therapy (LSR 0.89 0.1 vs. 0.95 0.1; p=0.038). PGART LSR values within groups not (p=0.46, p=0.37, respectively). Both drugs generally well tolerated; patients receiving reported less side effects than those group (0% 14,2%, respectively, p=0.037). Etoricoxib clinically effective providing magnitude comparable fewer effects. Effective phase such sports-related may be helpful morbidity capabilities associated performance like stiffness.