Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice.

作者: John S. House , Cody E. Nichols , Huiling Li , Christina Brandenberger , Rohan S. Virgincar

DOI: 10.1152/AJPLUNG.00495.2016

关键词:

摘要: Human genome-wide association studies have identified over 50 loci associated with pulmonary function and related phenotypes, yet follow-up to determine causal genes or variants are rare. S...

参考文章(50)
Alfredo J. Garcia, Sebastien Zanella, Henner Koch, Atsushi Doi, Jan-Marino Ramirez, Chapter 3--networks within networks: the neuronal control of breathing. Progress in Brain Research. ,vol. 188, pp. 31- 50 ,(2011) , 10.1016/B978-0-444-53825-3.00008-5
Scherle W, A simple method for volumetry of organs in quantitative stereology. Mikroskopie. ,vol. 26, pp. 57- 60 ,(1970)
Sharath S. Hegde, Richard M. Eglen, Peripheral 5-HT4 receptors. The FASEB Journal. ,vol. 10, pp. 1398- 1407 ,(1996) , 10.1096/FASEBJ.10.12.8903510
G. D. Funk, J. C. Smith, J. L. Feldman, Generation and transmission of respiratory oscillations in medullary slices: role of excitatory amino acids Journal of Neurophysiology. ,vol. 70, pp. 1497- 1515 ,(1993) , 10.1152/JN.1993.70.4.1497
Carl Potenzieri, Sonya Meeker, Bradley J. Undem, Activation of mouse bronchopulmonary C-fibres by serotonin and allergen-ovalbumin challenge. The Journal of Physiology. ,vol. 590, pp. 5449- 5459 ,(2012) , 10.1113/JPHYSIOL.2012.237115
A. De Troyer, J. C. Yernault, D. Rodenstein, Effects of vagal blockade on lung mechanics in normal man Journal of Applied Physiology. ,vol. 46, pp. 217- 226 ,(1979) , 10.1152/JAPPL.1979.46.2.217
Patrice G. Guyenet, Douglas A. Bayliss, Neural Control of Breathing and CO2 Homeostasis Neuron. ,vol. 87, pp. 946- 961 ,(2015) , 10.1016/J.NEURON.2015.08.001
Christina Brandenberger, Matthias Ochs, Christian Mühlfeld, Assessing particle and fiber toxicology in the respiratory system: the stereology toolbox Particle and Fibre Toxicology. ,vol. 12, pp. 35- 35 ,(2015) , 10.1186/S12989-015-0110-8
John S. House, Huiling Li, Laura M. DeGraff, Gordon Flake, Darryl C. Zeldin, Stephanie J. London, Genetic variation in HTR4 and lung function: GWAS follow-up in mouse The FASEB Journal. ,vol. 29, pp. 323- 335 ,(2015) , 10.1096/FJ.14-253898
B. J. Undem, The Role of Vagal Afferent Nerves in Chronic Obstructive Pulmonary Disease Proceedings of the American Thoracic Society. ,vol. 2, pp. 355- 360 ,(2005) , 10.1513/PATS.200504-033SR