作者: Nathan T. Connell , Jeremy S. Abramson
DOI: 10.1128/9781555816803.CH8
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摘要: Immunodeficiency associated with the human immunodeficiency virus (HIV) has been an increased risk of malignancy since dawn AIDS epidemic. Non-Hodgkin lymphoma (NHL) and invasive cervical cancer were subsequently identified to be among HIV-infected individuals classified along Kaposi sarcoma (KS) as AIDS-defining illnesses, though numerous additional malignancies have found enriched patients living HIV/AIDS but are not considered illnesses. The association NHL HIV infection was evident early in epidemic, when unusually high number lymphomas appeared young men registries California. majority AIDS-related (ARL) will present a these factors present, placing most high-risk category. Multicentric Castleman disease (MCD) is uniformly HHV-8, pathologically benign, may occur concurrently or progress independently demonstrate rapid progression result death. Anogenital squamous cell neoplasms third common subtype HIV-associated oncogenic serotypes HPV, commonly HPV-16, -18, -19. A other malignancies, including cancers lung, liver, prostate, testes, skin, others, frequency HIV-positive patients, this trend continues introduction highly active antiretroviral therapy (HAART).