A systematic assessment of the quality of reporting for platelet transfusion studies.

摘要: BACKGROUND: As evidence-based medicine assumes increasing importance, there is a need for high-quality reporting of clinical studies. A recent review platelet (PLT) studies indicated variability in reporting. We undertook critical analysis PLT transfusion to determine the quality reporting. STUDY DESIGN AND METHODS: systematic MEDLINE search was performed identify articles. Relevant observational (OBS) were critiqued using STROBE checklist and randomized controlled trials (RCTs) CONSORT checklist. Studies further evaluated with PLT-specific developed by authors. Observations analyzed descriptively Pareto analysis. RESULTS: total 772 articles identified search. Eighty-six (23 RCTs 63 OBS) met eligibility criteria. All RCTs, similar number OBS (24), randomly selected analysis. reported scientific background rationale, key results, outcomes. frequently did not consider bias confounders. explain bias, interim analyses, stopping rules, success blinding, or weaknesses multiple analyses. The critique found many adequately basics product, increment, reactions. failed report specific details compatibility, product preparation, use other blood products. CONCLUSION: Recently published share common strengths weaknesses. may be improved providing guidelines authors journal editors that list essential elements well-reported study transfusion.