Antitumor Immunity as Therapy for Human Cancer

摘要: Over the past few decades, an enormous body of knowledge has emerged concerning mechanisms implicated in structural and functional organization immune system; development tumors; manipulation cells, proteins, genetic material. Included remarkable progress is comprehension requirements for initiation execution T cell-mediated immunity; clarification pathways antigen (Ag) processing presentation; identification characterization tumor Ags; understanding principles organization, regulation, synthesis molecular structures. In parallel, major technological strides have been made, resulting routine practice formerly impossible manipulation, multiplication, modification molecules, genes.