Increased risk for cardiovascular mortality among malnourished end-stage renal disease patients

摘要: Abstract Background: Studies have shown that protein-energy malnutrition (PEM) is a strong predictor of total mortality among patients with end-stage renal disease (ESRD). The aim this study to assess the relationship between nutritional indices and cardiovascular (CV) ESRD by using data from US Renal Data System (USRDS) Dialysis Morbidity Mortality Study Wave I (DMMS-1). Methods: Demographic medical were abstracted 5,058 who participated in USRDS DMMS-1. Nutritional measurements interest included subjective assessment malnutrition, serum albumin level, body mass index (BMI), cholesterol level. provided follow-up on through July 1998. Cox proportional hazard model was used estimate risk for CV death associated markers. Results: 39% greater each 1-g/dL (10-g/L) decrement level (95% confidence interval [CI], 1.20 1.60; P = 0.026). In addition, change levels over time significantly mortality. For 0.1-g/dL (1-g/L) per month, 2.24-fold CI, 1.65 3.02; Conclusion: Both PEM at baseline worsening are death. This finding persists dialysis without preexisting CVD baseline. © 2002 National Kidney Foundation, Inc.