Original research article Preliminary evaluation of deslorelin, a GnRH agonist for contraception of the captive variable flying fox Pteropus hypomelanus ☆

摘要: Background: This study was conducted to the effects of a gonadotropin-releasing hormone (GnRH) agonist, deslorelin, on luteinizing (LH), testosterone (males), semen characteristics and pregnancy in variable flying fox Pteropus hypomelanus. Study Design: Male (n=3) female (n=5) bats received 4.7-mg implant were housed with untreated (eight females three males, respectively). Plasma collected twice monthly analyzed for concentrations, from treated males 1 month preimplantation, 3 months postimplantation 4 postimplantation. Results: Administration GnRH challenge showed an attenuated response (n=4), but not male bats. LH lower versus (p=.04), females. Testosterone (pb.001). Spermic ejaculates obtained although no became pregnant during 8-month study. One 6 after implantation. Conclusion: Deslorelin is useful reversible contraceptive P.