Prevalence and characteristics of screen-detected prostate carcinomas at low prostate-specific antigen levels: aggressive or insignificant?
作者： Claartje Gosselaar , Monique J. Roobol , Fritz H. Schroder
DOI: 10.1111/J.1464-410X.2005.05324.X
关键词:
摘要: SUMMARY Screening for prostate cancer at low prostate-specific antigen (PSA) levels (≤4.0 ng/mL) risks detecting clinically insignificant cancers, which are of no threat to the man. In this review we evaluate prevalence and tumour characteristics detected PSA levels, comparing screening studies, cystoprostatectomy series autopsy data. The favourable tumours detectable very seem justify conclusion that an unknown but sizeable proportion cancers found biopsy insignificant.
mysciencework.com参考文章(46)
Bogdanowicz Jf, Bentvelsen Fm, Oosterom R, Schroeder Fh, Evaluation of prostate-specific antigen and prostatic acid phosphatase in untreated prostatic carcinoma and benign prostatic hyperplasia. Scandinavian Journal of Urology and Nephrology. ,vol. 138, pp. 97- 103 ,(1991)
Gleason Df, Classification of prostatic carcinomas. Cancer chemotherapy reports. ,vol. 50, pp. 125- 128 ,(1966)
Bruce A. Lowe, Margaret B. Listrom, Incidental Carcinoma of the Prostate: An Analysis of the Predictors of Progression The Journal of Urology. ,vol. 140, pp. 1340- 1344 ,(1988) , 10.1016/S0022-5347(17)42039-8
Scardino Pt, Early detection of prostate cancer. Urologic Clinics of North America. ,vol. 16, pp. 635- 655 ,(1989)
W.A. Sakr, G.P. Haas, B.F. Cassin, J.E. Pontes, J.D. Crissman, The Frequency of Carcinoma and Intraepithelial Neoplasia of the Prostate in Young Male Patients The Journal of Urology. ,vol. 150, pp. 379- 385 ,(1993) , 10.1016/S0022-5347(17)35487-3
Albert E. Hirst, R. Theodore Bergman, Carcinoma of the prostate in men 80 or more years old Cancer. ,vol. 7, pp. 136- 141 ,(1954) , 10.1002/1097-0142(195401)7:1<136::AID-CNCR2820070114>3.0.CO;2-C
Thomas A. Stamey, Biological determinants of cancer progression in men with prostate cancer. JAMA. ,vol. 281, pp. 1395- 1400 ,(1999) , 10.1001/JAMA.281.15.1395
Vivek Narain, Fernando J. Bianco, David J. Grignon, Wael A. Sakr, J. Edson Pontes, David P. Wood, How accurately does prostate biopsy Gleason score predict pathologic findings and disease free survival? The Prostate. ,vol. 49, pp. 185- 190 ,(2001) , 10.1002/PROS.1133
WILLIAM J. CATALONA, GEORG BARTSCH, HARRY G. RITTENHOUSE, CINDY L. EVANS, HARRY J. LINTON, WOLFGANG HORNINGER, HELMUT KLOCKER, STEPHEN D. MIKOLAJCZYK, SERUM PRO-PROSTATE SPECIFIC ANTIGEN PREFERENTIALLY DETECTS AGGRESSIVE PROSTATE CANCERS IN MEN WITH 2 TO 4 NG/ML PROSTATE SPECIFIC ANTIGEN The Journal of Urology. ,vol. 171, pp. 2239- 2244 ,(2004) , 10.1097/01.JU.0000127737.94221.3E
Thomas A. Stamey, Fuad S. Freiha, John E. McNeal, Elise A. Redwine, Alice S. Whittemore, Hans-Peter Schmid, Localized prostate cancer. Relationship of tumor volume to clinical significance for treatment of prostate cancer Cancer. ,vol. 71, pp. 933- 938 ,(1993) , 10.1002/1097-0142(19930201)71:3+<933::AID-CNCR2820711408>3.0.CO;2-L