Urothelial cancer gene regulatory networks inferred from large-scale RNAseq, Bead and Oligo gene expression data

摘要: Background Urothelial pathogenesis is a complex process driven by an underlying network of interconnected genes. The identification novel genomic target regions and gene targets that drive urothelial carcinogenesis crucial in order to improve our current limited understanding cancer (UC) on the molecular level. inference genome-wide regulatory networks (GRN) from large-scale expression data provides promising approach for detailed investigation structure associated carcinogenesis.