The effects of clinical interventions on health-related quality of life in multiple sclerosis: a meta-analysis.
作者： Ayse Kuspinar , Ana Maria Rodriguez , Nancy E Mayo
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摘要: The objective is to estimate the extent which existing health care interventions designed specifically target health-related quality of life (HRQL) in persons with multiple sclerosis (MS) achieve this aim. structured literature search was conducted using electronic databases including Ovid MEDLINE, EMBASE, Cumulative Index Nursing and Allied Health Literature Cochrane Central Register Controlled Trial, for years 1960 2011. methodological selected randomized controlled trials (RCTs) assessed Collaboration’s recommended domain-based method. Effect size (ES) used measure effect each intervention on HRQL. studies were combined a random-effects model account inter-study variation. Heterogeneity tested I-test publication bias funnel plots Egger weighted regression statistic. Thirty-nine RCTs met criteria, all acceptable quality. Six...
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