Bioengineered corneas--the promise and the challenge.

作者: Ivan R. Schwab , R. Rivkah Isseroff

DOI: 10.1056/NEJM200007133430211

关键词:

摘要: The promise of bioengineered replacements for diseased or damaged tissues has become a reality, notably skin and cartilage. article by Tsai et al. in this issue the Journal 1 demonstrates nascent form technology that may provide new tool reconstructing ocular surfaces previously would have been unrepairable. Conditions such as Stevens–Johnson syndrome, cicatricial pemphigoid, chemical burns, among others, can severely compromise cause catastrophic visual loss otherwise healthy eyes; problems afflict thousands patients North America every year.2 global burden blindness . . .

参考文章(10)
Shigeto Shimmura, Minako Kaido, Kazuo Tsubota, Jun Shimazaki, Naoshi Shinozaki, Kimiyoshi Tsuji, Masao Hagihara, Batmunkh Munkhbat, Evidence of long-term survival of donor-derived cells after limbal allograft transplantation. Investigative Ophthalmology & Visual Science. ,vol. 40, pp. 1664- 1668 ,(1999)
Edward J. Holland, Gary S. Schwartz, EPITHELIAL STEM-CELL TRANSPLANTATION FOR SEVERE OCULAR-SURFACE DISEASE The New England Journal of Medicine. ,vol. 340, pp. 1752- 1753 ,(1999) , 10.1056/NEJM199906033402208
P. V. Prasad, Sasikala D. P. Potluri, Influence of proline and hydroxyproline on salt-stressed axillary bud cultures of two varieties of potato (Solanum tuberosum) In Vitro Cellular & Developmental Biology – Plant. ,vol. 32, pp. 47- 50 ,(1996) , 10.1007/BF02823013
Christopher Jenkins, Stephen Tuft, Christopher Liu, Roger Buckley, None, Limbal transplantation in the management of chronic contact-lens-associated epitheliopathy Eye. ,vol. 7, pp. 629- 633 ,(1993) , 10.1038/EYE.1993.145
Ray Jui-Fang Tsai, Lien-Min Li, Jan-Kan Chen, Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. The New England Journal of Medicine. ,vol. 343, pp. 86- 93 ,(2000) , 10.1056/NEJM200007133430202
J. M. Slack, Stem Cells in Epithelial Tissues Science. ,vol. 287, pp. 1431- 1433 ,(2000) , 10.1126/SCIENCE.287.5457.1431
George Cotsarelis, Shih-Zen Cheng, Gang Dong, Tung-Tien Sun, Robert M. Lavker, Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell. ,vol. 57, pp. 201- 209 ,(1989) , 10.1016/0092-8674(89)90958-6
Graziella Pellegrini, Carlo E Traverso, Adriano Tito Franzi, Mario Zingirian, Ranieri Cancedda, Michele De Luca, Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium The Lancet. ,vol. 349, pp. 990- 993 ,(1997) , 10.1016/S0140-6736(96)11188-0