Natural phosphate-supported Cu( ii ), an efficient and recyclable catalyst for the synthesis of xanthene and 1,4-disubstituted-1,2,3-triazole derivatives

摘要: Cu(NO3)2 supported on natural phosphate, Cu(II)/NP, was prepared by co-precipitation and applied as a heterogeneous catalyst for synthesizing xanthenes (2–3 h, 85–97%) through Knoevenagel–Michael cascade reaction of aromatic aldehydes with 1,3-cyclic diketones in ethanol under refluxing conditions. It further used regioselective synthesis 1,4-disubstituted-1,2,3-triazoles (1–25 min, 95–99%) via three-component between organic halides, alkynes sodium azide methanol at room temperature. The proposed catalyst, characterized using X-ray fluorescence, diffraction, Fourier-transform infrared spectroscopy, scanning electron microscopy, Brunauer–Emmett–Teller, Barrett–Joyner–Halenda inductively coupled plasma analyses. Compared to other reports literature, the reactions took place simple co-precipitation, having short time ( 85%), high recyclability (>5 times) without significant decrease inherent property selectivity catalyst. protocols provided economic environmental advantages.