A New Microcontroller-Based Human Brain Hypothermia System

作者: Metin Kapıdere , Raşit Ahıska , İnan Güler

DOI: 10.1007/S10916-005-6107-2

关键词:

摘要: Many studies show that artificial hypothermia of brain in conditions anesthesia with the rectal temperature lowered down to 33?C produces pronounced prophylactic effect protecting from anoxia. Out methods employed now clinical practice for reducing oxygen consumption by cerebral tissue, most efficacious is craniocerebral (CCH). It finding even more extensive application cardiovascular surgery, neurosurgery, neurorenimatology and many other fields medical practice. In this study, a microcontroller-based designed human system (HBHS) constructed. The intended cooling heating brain. HBHS consists thermoelectric hypothermic helmet, control power unit. Helmet controlled 8-bit PIC16F877 microcontroller which programmed using MPLAB editor. Temperature converted 10-bit digital automatically preset values have been already entered microcontroller. Calibration working range tested. helmet between ?5 +46?C microcontroller, accuracy ± 0.5?C.

参考文章(8)
Metin Kapidere, Serdar Müldür, İnan Güler, Control of Dental Prosthesis System With Microcontroller Journal of Medical Systems. ,vol. 24, pp. 119- 129 ,(2000) , 10.1023/A:1005520931001
Moon Chung, N.M. Miskovsky, P.H. Cutler, Nalin Kumar, V. Patel, Theoretical analysis of a field emission enhanced semiconductor thermoelectric cooler Solid-state Electronics. ,vol. 47, pp. 1745- 1751 ,(2003) , 10.1016/S0038-1101(03)00185-0
Jaroslav Mackerle, Finite element analyses and simulations in biomedicine: a bibliography (1985‐1999) Engineering Computations. ,vol. 17, pp. 813- 856 ,(2000) , 10.1108/02644400010352270
Hushan Ao, Jon K. Moon, Hironari Tanimoto, Yuji Sakanashi, Hidenori Terasaki, Jugular vein temperature reflects brain temperature during hypothermia. Resuscitation. ,vol. 45, pp. 111- 118 ,(2000) , 10.1016/S0300-9572(00)00154-4
Joji Inamasu, Yoshiki Nakamura, Kiyoshi Ichikizaki, Induced hypothermia in experimental traumatic spinal cord injury: an update Journal of the Neurological Sciences. ,vol. 209, pp. 55- 60 ,(2003) , 10.1016/S0022-510X(02)00463-X
P. VanBaren, E.S. Ebbini, Multipoint temperature control during hyperthermia treatments: theory and simulation IEEE Transactions on Biomedical Engineering. ,vol. 42, pp. 818- 827 ,(1995) , 10.1109/10.398643
J.K. Potocki, H.S. Tharp, Reduced-order modeling for hyperthermia control IEEE Transactions on Biomedical Engineering. ,vol. 39, pp. 1265- 1273 ,(1992) , 10.1109/10.184702
Suzanne DeBow, Frederick Colbourne, Brain temperature measurement and regulation in awake and freely moving rodents. Methods. ,vol. 30, pp. 167- 171 ,(2003) , 10.1016/S1046-2023(03)00080-X