Ingestion of branched-chain amino acids and tryptophan during sustained exercise in man: failure to affect performance.

摘要: 1. An increased uptake of tryptophan in the brain may increase serotoninergic activity and recently has been suggested to be a cause fatigue during prolonged exercise. The present study, therefore, investigates whether ingestion or competing branched-chain amino acids (BCAAs) affect performance. Ten endurance-trained male athletes were studied cycle exercise at 70-75% maximal power output, while ingesting, ad random double-blind, drinks that contained 6% sucrose (control) supplemented with (1) (3 g l-1), (2) low dose BCAA (6 l-1) (3) high (18 l-1). 2. These treatments greatly plasma concentration respective acids. Using kinetic parameters transport human capillaries, supplements estimated reduce exhaustion by 8-12%, caused 7- 20-fold increase. Exercise time was not different between (122 +/- 3 min). 3. data suggest manipulation supply either no additional effect upon exhaustive functionally does contribute mechanisms fatigue.