Method for diagnosis of alzheimer's disease with determination of LASP-1 immunoreactivity

作者: Christina Fischer-Schulz , Joachim Struck , Andreas Bergmann

DOI:

关键词:

摘要: Method for early diagnosis and diagnosis, prognosis assessment of the severity therapy-accompanying monitoring inflammatory diseases infections, in particular sepsis-like systemic infections Alzheimer's disease, which presence and/or amount protein LASP-1 (SEQ ID NO:1) or LAP-1 NO:16) an immunoreactive fragment one these proteins free protein-bound form is determined, preferably as immunoreactivity, a biological fluid, optionally tissue sample, patient, conclusions are drawn with respect to presence, expected course, success therapy disease infection from determined.

参考文章(55)
Cem Gabay, Irving Kushner, Acute-Phase Proteins and Other Systemic Responses to Inflammation The New England Journal of Medicine. ,vol. 340, pp. 448- 454 ,(1999) , 10.1056/NEJM199902113400607
Begona Aguado, Robert Duncan Campbell, Lysophosphatidic acid acyltransferase gene and its use ,(1997)
Andrew Remppis, Hugo A Katus, Therapie der Herzinsuffizienz ,(1999)
Edward Abraham, Anti-TNF Strategies Sepsis. ,vol. 1, pp. 19- 20 ,(1997) , 10.1023/A:1009703132434
Valérie Schreiber, Christel Moog-Lutz, Catherine H. Régnier, Marie-Pierre Chenard, Hélène Boeuf, Jean-Luc Vonesch, Catherine Tomasetto, Marie-Christine Rio, Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions. Molecular Medicine. ,vol. 4, pp. 675- 687 ,(1998) , 10.1007/BF03401929
Fong-Ying Tsai, Rachel Meyers, 53320, a novel human acyltransferase and uses therefor ,(2001)