Fluconazole for the prevention and treatment of tinea gladiatorum

摘要: Background. Tinea gladiatorum is a common problem in competitive wrestling. It impacts on wrestler's ability to compete. Several methods have been advocated prevent these infections; however, no well-designed study of pharmacologic prophylaxis has conducted. Methods. In double blind placebo-controlled trial during the 1998 1999 regular wrestling season, wrestlers were randomized receive 100 mg fluconazole once weekly or placebo weekly. Those not involved treated as second control group. The effects also examined by assessing treatment clinical infections with 200 for 4 weeks. Results. There was significantly smaller incidence infection those given (6%) than receiving (22%) and phase (18%) (P < 0.05). significant reduction total number group Prophylaxis did impact severity disease, if contracted, when compared participants who contracted tinea corporis. Of 21 positive cultures, 14 able their isolates identified Trichophyton tonsurans. Conclusions. Fluconazole effective safe primary prevention gladiatorum. We must now define what population would be warranted.