Hemostasis and Thrombosis
作者： Richard C. Becker , Deepak Voora , Svati H. Shah
DOI: 10.1016/B978-0-12-382227-7.00052-5
关键词:
摘要: Hemostasis, as a highly regulated teleological process, and blood coagulation are cell surface, biochemical events designed not only to stem the loss of following vascular injury through fibrin formation, but also provide necessary cellular protein constituents for growth repair. Conceptually, represents complex yet well-coordinated series which involve tissue factor-bearing cells platelets. The initiation propagation phases catalyzed by thrombin in small (nM) large concentrations, respectively. heritability is well known can manifest clinically either predisposition bleeding (impaired hemostasis) or clotting (thrombophilia). Our chapter frames fundamental constructs practical terms, including genetic determinants, environmental influences, impact race, culture ethnicity, use testing patient population screening, guidance management routine care.
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