High prevalence of Helicobacter pylori infection in shepherds

摘要: It has been suggested that Helicobacter pylori infection may, in some instances, be a zoonosis. The aim of this study was to evaluate the prevalence H. Sardinian shepherds and their families relation exposure sheep dogs. control group blood donors completed detailed questionnaires regarding demographics, childhood current economic status, presence symptoms related upper gastrointestinal tract. status determined by sensitive ELISA for anti-H. IgG western blot anti-CagA IgG. A subgroup had endoscopy with biopsy assess severity gastritis. approached 100% positively animal contact (98% shepherds, 73% family members without regular direct compared 43% donors) (P < 0.001). Importantly, shared same but choose different careers (e.g., teachers, nurses, business) did not have sheep. In conclusion, is among highest world associated These results suggest cycle might, certain circumstances, include phases environment, animals (sheep or dogs) human beings.