Minority Recruitment in the Prostate Cancer Prevention Trial

摘要: Abstract PURPOSE: African American men have a higher prostate cancer risk profile than that of other in the United States. The purpose this manuscript is to summarize challenges associated with enrolling and randomizing minority participants Prostate Cancer Prevention Trial (PCPT). METHODS: PCPT randomized trial finasteride versus placebo for preventing healthy age 55 years older; it coordinated by Southwest Oncology Group. describes demographic lifestyle characteristics sample (18,882 men) four racial ethnic groups (Caucasian, American, Hispanic, other). comprised 4% total compared our goal 8%. Minority recruitment was emphasized through Study Manual training occurred at activation. Supplemental activities were initiated year after study activation continued end accrual period. as follows: presentations seminars (held during twice yearly Group meetings); distribution additional materials; engagement consultants recruitment; production Recruitment Manual; small pilot involving outreach recruiters five sites. RESULTS: helpful implementing project suggesting reviewing materials recruitment. five-site did not increase either enrollment or randomization minorities (with possible exception one site). CONCLUSIONS: We suggest long-term perspective required successful clinical trials. Likewise, extensive efforts must be ready implement