Use of nasal provocation test in the diagnostics of occupational rhinitis.
作者： Liisa Airaksinen , Risto Voutilainen , Markku Vanhanen , Timo Tuomi , Elina Toskala
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摘要: Objectives: The purpose of the study was to evaluate usefulness and clinical value nasal provocation test (NPT) with various allergens non-IgE-mediated irritants in diagnostics assessing occupational rhinitis. Methods: A large number data from patients suspected rhinitis evaluated retrospectively. results tests different agents, as well correlation scoring weighed mucus secretion, were analyzed. Results: Altogether 507 NPTs done three years 165 persons. In total, 39% allergen provocations (125/318) positive. most common positive reactions against flours, animal epithelia, storage mites plants. Wood dusts, mainly through reactions, gave 50% results. Positive moulds observed sensitized patients. Altogether, 10% control weighting secretion added sensitivity NPT. Conclusions: NPT is an essential standard tool allergic rhinitis; however it needs be context medical work history knowledge sensitization. Although expensive laborious, safe easy for patient. We still need reliable diagnostic tools non-allergic work-related SUMMARY
researchgate.net 参考文章(18)
Lasse Kanerva, Eero Vaheri, Occupational allergic rhinitis in Finland International Archives of Occupational and Environmental Health. ,vol. 64, pp. 565- 568 ,(1993) , 10.1007/BF00517702
Morgan Andersson, Lennart Greiff, Christer Svensson, Carl Persson, Various methods for testing nasal responses in vivo: a critical review. Acta Oto-laryngologica. ,vol. 115, pp. 705- 713 ,(1995) , 10.3109/00016489509139391
T. A. Skovsted, V. Schlunssen, I. Schaumburg, P. Wang, P. Staun-olsen, P. S. Skov, Only few workers exposed to wood dust are detected with specific IgE against pine wood. Allergy. ,vol. 58, pp. 772- 779 ,(2003) , 10.1034/J.1398-9995.2003.00127.X
T. HAAHTELA, A. LAHDENSUO, Non-specific reactions caused by diluents containing glycerol in nasal and bronchial challenge tests. Clinical & Experimental Allergy. ,vol. 9, pp. 225- 227 ,(1979) , 10.1111/J.1365-2222.1979.TB01546.X
Kari Reijula, Marina Leino, Helena Mussalo-Rauhamaa, Marjo Nikulin, Harri Alenius, Jari Mikkola, Peter Elg, Osmo Kari, Soili Mäkinen-Kiljunen, Tari Haahtela, IgE-mediated allergy to fungal allergens in Finland with special reference to Alternaria alternata and Cladosporium herbarum. Annals of Allergy Asthma & Immunology. ,vol. 91, pp. 280- 287 ,(2003) , 10.1016/S1081-1206(10)63531-4
Maija L Hytönen, Eeva L Sala, Henrik O Malmberg, Henrik Nordman, Acoustic Rhinometry in the Diagnosis of Occupational Rhinitis American Journal of Rhinology. ,vol. 10, pp. 393- 398 ,(1996) , 10.2500/105065896781794798
Jan Gosepath, Ronald G. Amedee, Wolf J. Mann, Nasal provocation testing as an international standard for evaluation of allergic and nonallergic rhinitis. Laryngoscope. ,vol. 115, pp. 512- 516 ,(2005) , 10.1097/01.MLG.0000149682.56426.6B
B. Kanceljak-Macan, J. Macan, D. Plavec, T. Klepac, S. Milkovic-Kraus, The 3 mm skin prick test (SPT) threshold criterion is not reliable for Tyrophagus putrescentiae: the re-evaluation of SPT criterion to dust mites. Allergy. ,vol. 57, pp. 1187- 1190 ,(2002) , 10.1034/J.1398-9995.2002.23730.X
Robert E Esch, Manufacturing and standardizing fungal allergen products. The Journal of Allergy and Clinical Immunology. ,vol. 113, pp. 210- 215 ,(2004) , 10.1016/J.JACI.2003.11.024
Miroslav Ceska, Ulf Lundkvist, A new and simple radioimmunoassay method for the determination of IgE Immunochemistry. ,vol. 9, pp. 1021- 1030 ,(1972) , 10.1016/0019-2791(72)90112-7