Anti-anginal Effect of the Calcium Antagonist Gallopamil
作者： V. Mitrovíc , L. Niemelä , H. Neuss , M. Schlepper
DOI: 10.1007/978-3-662-07364-3_11
关键词:
摘要: The beneficial effect of calcium antagonists on coronary spasms has, in recent years, led to these drugs being used increasingly for the treatment patients with heart disease (Maseri 1980; Mellemgaard et al. 1978). Because there are distinct differences pharmacokinetics and pharmacodynamics substances available it is necessary establish precisely recommended dosages dosage intervals each new preparation this group. antagonist gallopamil (Procorum) a methoxy derivative verapamil which was found animals be three five times more potent than verapamil. Our studies showed that peak plasma concentration occurs approximately 1–2h after administration (Neuss 1982). controlled study reported here investigate anti-anginal disease.
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sci-hub.st 参考文章(5)
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