Carbohydrate counting with an automated bolus calculator helps to improve glycaemic control in children with type 1 diabetes using multiple daily injection therapy: an 18-month observational study.

摘要: Abstract Aims This study aimed to investigate the effect of carbohydrate counting (carbC), with or without an automated bolus calculator (ABC), in children type 1 diabetes treated multiple daily insulin injections. Methods We evaluated 85 children, aged 9–16 years, diabetes, divided into four groups: controls ( n  = 23), experienced carbC  = 19), carbC + ABC  = 18) and non-experienced  = 25). Glycated haemoglobin (HbA1c), use, glycaemic variability – as high blood glucose index (HBGI) low (LBGI) were assessed at baseline after 6 18 months. Results At baseline, age, disease duration, BMI, HbA1c, HBGI (but not LBGI; p  = 0.020) similar for all groups. After months, HbA1c improved from although significantly patients using ABC (according manufacturer's recommendations) 7.14 ± 0.41% months vs. 7.35 ± 0.53%  = 0.136) experience 7.61 ± 0.62% 7.95 ± 0.99%  = 0.063). Patients had a better  = 0.001) slightly worse LBGI  = 0.010) than those ABC. settings then personalised. further improvements seen ABC, especially group (−0.42% baseline;  = 0.018). Conclusions CarbC helped improve control use led greater compared only carbC, regardless carbC.