Hierarchies of transcriptional regulation during liver regeneration
作者： Svitlana Kurinna , Michelle Craig Barton
DOI: 10.1016/B978-0-12-385233-5.00007-6
关键词:
摘要: The remarkable capacity of the liver to regenerate after severe injury or disease has excited interest for centuries. goal harnessing this process in treatment disease, and appreciation parallels between regeneration tumor development liver, remain a major driver research area. Studies as model system offer view intricate precisely timed regulatory pathways that drive toward completion. Successful mass demands hierarchal well-controlled balance proliferative metabolic functions, which is orchestrated by signaling regulation transcription factors. Control these cascades transcriptional activities, necessary induction, renewal, cessation growth, are focus chapter.
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