Evidence that the Ciliary Inhibitor of Cystic Fibrosis is not an Antibody
作者： Victoria Herzberg , Lynette Calvert , Barbara H. Bowman
DOI: 10.1172/JCI107468
关键词:
摘要: An inhibitor of ciliary activity is present in the serum cystic fibrosis (CF) patients and heterozygotes. Fractionation CF has indicated that associated with IgG fraction. This study compared to rabbit antibody preparations directed against oyster cilia. The aim this investigation was determine whether inhibitory mechanism related a typical immunological reaction. Results from experiments utilizing fluorescent techniques demonstrated an antiserum ciliated epithelium binds immunologically both human bronchial epithelial tissue. immunofluorescent tracing, passive hemagglutination, double immunodiffusion, papain digestion, however, interaction between cilia not antigen-antibody
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