Risk Factors for Age-Related Maculopathy

摘要: Objective To describe the risk factors and associated population attributable for age-related maculopathy (ARM) macular degeneration(AMD) in Australians aged 40 years older. Methods Residents were recruited from 9 randomly selected urban clusters 4 rural Victoria, Australia. At locally established test sites, following information was collected: visual acuity, medical health history, lifetime sunlight exposure, dietary intake, fundus photographs. Age-related AMD graded photographs using an international classification grading system. Backwards logistic regression used to identify independent ARM AMD. Results The participation rate 83% (n = 3271) among residents 92% 1473) residents. Gradable of either eye available 4345 (92%) 4744 participants. There 656 cases ARM, giving a weighted prevalence 15.1% (95% confidence limit [CL], 13.8, 16.4); there 30 AMD, 0.69% CL, 0.33, 1.03). In multiple regression, as follows: age (odds ratio [OR], 1.23; 95% 1.17, 1.29), smoked cigarettes longer than (OR, 2.39; 1.02, 5.57), ever taken angiotensin-converting enzyme inhibitors 3.26; 1.33, 8.01). magnitude all these slightly less having blood cholesterol–lowering medications also significant 1.67; 1.12, 2.47;P= .001). Conclusion Smoking is only modifiable factor many environmental systemic that assessed.