Spin Trapping Studies of the Influence of Alcohol on Lipid Peroxidation

作者: F. F. Ahmad , D. L. Cowan , A. Y. Sun

DOI: 10.1007/978-1-4612-4514-8_19

关键词:

摘要: The discovery by Fridovitch and coworkers (33) in the late 1960s of an enzyme (superoxide dismutase) specific for catalytic removal superoxide (O2 -) radical has led to intense research on effects naturally occurring free radicals biological systems. Since that time, many endogenous enzymatic reactions have been found potentially damaging intermediate oxidation states produced metabolism oxygen [superoxide -), hydrogen peroxide (H2O2), hydroxyl (∙OH) radicals]. These “active” molecules implicated a variety human disease including cancer aging (17,20,22).

参考文章(32)
David Ross, Glutathione, free radicals and chemotherapeutic agents Pharmacology & Therapeutics. ,vol. 37, pp. 231- 249 ,(1988) , 10.1016/0163-7258(88)90027-7
G J Quinlan, J M Gutteridge, Malondialdehyde formation from lipid peroxides in the thiobarbituric acid test: the role of lipid radicals, iron salts, and metal chelators. Biotechnology and Applied Biochemistry. ,vol. 5, pp. 293- 299 ,(1983)
Catherine Rice-Evans, Free radicals, cell damage and disease Richelieu Press. ,(1986)
R. S. Sohal, Donald Armstrong, Richard G. Cutler, Free Radicals in Molecular Biology, Aging, and Disease ,(1984)
William A. Pryor, Free Radicals in Biology ,(1976)
Edward G. Janzen, [22] Spin trapping Methods in Enzymology. ,vol. 105, pp. 188- 198 ,(1984) , 10.1016/S0076-6879(84)05025-4
Robert A. Floyd, C.Ann Lewis, Peter K. Wong, [27] High-pressure liquid chromatography-electrochemical detection of oxygen free radicals Methods in Enzymology. ,vol. 105, pp. 231- 237 ,(1984) , 10.1016/S0076-6879(84)05030-8
P B McCay, E K Lai, J L Poyer, C M DuBose, E G Janzen, Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro. Journal of Biological Chemistry. ,vol. 259, pp. 2135- 2143 ,(1984) , 10.1016/S0021-9258(17)43327-8
J. Imlay, S Linn, DNA damage and oxygen radical toxicity Science. ,vol. 240, pp. 1302- 1309 ,(1988) , 10.1126/SCIENCE.3287616
E. Albano, A. Tomasi, L. Goria-Gatti, G. Poli, V. Vannini, M. U. Dianzani, Free Radical Metabolism of Alcohols by Rat Liver Microsomes Free Radical Research Communications. ,vol. 3, pp. 243- 249 ,(1987) , 10.3109/10715768709069789