Chapter 10 Some properties of the sympathoinhibition from the caudal ventrolateral medulla oblongata in the cat

作者: K. Dembowsky , J. Czachurski , H. Seller

DOI: 10.1016/S0079-6123(08)62005-1

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摘要: Publisher Summary Neurons in the caudal ventrolateral medulla oblongata (CVLM) play an important role control of sympathetic activity. The excitation these neurons by small injections excitatory amino acids causes inhibition activity and a fall arterial blood pressure. This chapter presents study that clarifies question whether sympathoinhibition from CVLM is because post-synaptic or disfacilitation preganglionic (SPNs) first studying spinal pathway this inhibitory response. If its cord could be dissociated descending sympathoexcitatory rostral (RVLM) runs dorso- funiculus cord, would strong evidence against SPNs. Because more direct for either should provided intracellular recordings SPNs, has also been addressed recording SPNs intracellularly effects glutamate into on their membrane potential. It studied if noradrenaline acting α 2 -adrenergic receptors involved as transmitter involves afferent projection to hypothalamus cerebellum.

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